La Isifo sika-Addison ezinjeni, esingazi futhi ngegama le-hypoadrenocorticism, iyingxenye yesinye sezifo esine-sequelae esibi ezinjeni, yize ngenhlanhla yokwelashwa okufanele kakhulu, izinja ezithole ukuxilongwa kwalesi sifo zinethuba lokuthola ukuba nesikhathi sokuphila esijwayelekile ngokuphelele.
Uma sibona ukuthi isilwane sethu sigula kaningi futhi nemithi esiyinike yona ayibangeli mthelela, kungenzeka ukuthi ihlushwa yisifo i-Addison, kungalesi sizathu ukuthi kulesi sihloko sikulethela nonke imininingwane edingekayo mayelana ne- izimpawu, ukwelashwa nokunakekelwa yalesi sifo
Siyini isifo sika-Addison
Isifo sika-Addison ezinjeni, esinegama lesayensi hypoadrenocorticism, kuyisifo esibi kakhulu lokho kuthinta noma eyodwa noma zombili izindlala ze-adrenal zenja yethu, okuyizona ezitholakala ngqo ezinso.
Noma yini ebanga i- ukulimala kwezindlala ze-adrenal kungaba imbangela yesifo sika-Addison.
Izinja ezinalesi sifo azikwazi ukukhiqiza inani elidingekayo lamahomoni adrenal (aziwa kangcono njenge ukungasebenzi kwe-canine adrenal) ngakho-ke imele okuthile okubucayi ezicini eziningi zomsebenzi womzimba. Lokhu kubangela ukuthi amazinga kashukela, i-sodium, i-potassium kanye ne-chloride atholakala egazini awanakho ukulawula okudingekayo, okungadala ukoma emzimbeni kwenja yethu kanye nezinkinga ezinkulu kakhulu ezithweni ezibalulekile zomngane wethu onoboya, ngokukhethekile inhliziyo.
Yini Ebangela Isifo Sika-Addison Ezizinja
Ngokuvamile futhi cishe kuzo zonke izimo, yini engadala i- Isifo sika-Addison ezinjeni kuyinto engakaziwa.
Abahlengikazi bezilwane banokusola ukuthi ezimweni eziningi nalesi sifo kungenxa yomphumela wenqubo ezenzakalelayo. Isifo sika-Addison ngokufanayo kungabangelwa ngenxa yokubhujiswa kwendlala ye-adrenalKungaba isimila se-metastatic, isifo senhliziyo, ukopha, isifo se-granulomatous, ngama-adrenolytic agents, njenge-mitotane yezidakamizwa noma ngemithi ethile efana ne-trilostane, enekhono lokuvimbela ama-enzyme adrenal.
Uma kukhona okuvimba i- ukusebenza kahle kwezindlala ze-adrenal, umzimba awusenamandla okukhiqiza ama-glucocorticoids kanye nama-mineralocorticoids, ikakhulukazi i-aldosterone ne-cortisol. Ngakho-ke, lokhu kubangela inani elikhulu lezimpawu futhi ezimweni ezinzima kakhulu zezinja ezinesifo i-Addison, ukufa kuyenzeka.
Ososayensi abanalo ulwazi oluqondile lwe kungaba yini imbangela yesifo sika-AddisonKodwa-ke, noma iyiphi inja ngaphandle kohlobo noma nobukhulu inethuba lokuthola lesi sifo. Kodwa-ke, izinhlobo ezithile zezinja zithambekele kakhulu ekuthuthukiseni isifo sika-Addison futhi yilezi ezilandelayo:
- Iphinikhodi
- I-terrier emhlophe
- Umsele omkhulu
- U-Bearded Collie.
- Inja Yamanzi YasePutukezi
- INova Scotia terrier.
- I-Irish Soft Camera Wheaten Terrier
Isifo sika-Addison unamandla okuthinta izinja kungakhathalekile ukuthi ungowaluphi uhlobo, ubudala noma ubuliliKodwa-ke, kujwayelekile kakhulu ezinjeni ezincane, ezinsikazi nakulabo abaneminyaka ephakathi nendawo.
Izimpawu zesifo i-Addison
Lapho isifo sika-Addison sivela ezinjeni, senza kanjalo ngokuqhubekayo futhi imvamisa kunzima kakhulu ukuxilonga ngenxa yenani elikhulu lezimpawu ezihlobene nalesi sifo.
Ngokuvamile, izinja ezinesifo i-Addison zinamandla okuthuthukisa iziqephu ezinzima kakhulu ze-gastroenteritis, ukulahlekelwa isifiso sokudla, ukulahleka kancane kwesimo somzimba, futhi kungadala nengcindezi. Kubaluleke kakhulu ukuthi sikugcine engqondweni lokho Izimpawu ze-Addison's Disease in Dogs, ngoba lezi zingakhula noma zinciphe.
Ukukhiqizwa okwehlisiwe kwe-aldosterone kunomthelela obonakalayo emzimbeni. Lokhu kuyinto eholela ekuguqulweni kwamazinga e-serum we-sodium potassium kanye ne-chloride nalokho kungathinta izinso. Lokhu ngendlela efanayo kungadala izinkinga enhliziyweni nasesimisweni sokujikeleza kwegazi.
ICortisol ingenye ye- ama-hormone ama-steroid abaluleke kakhulu esithinteka yisifo i-Addison, naso esidlala indima ebaluleke kakhulu ezicutshini eziningi zomzimba wenja yethu. Lokhu kunesibopho sokulawula ukukhiqizwa kwe-glucose, kodwa futhi kulawula imetabolism, inesibopho sokudiliza amanoni namaprotheni, ilawula umfutho wegazi, ivuselele ukwakheka kwamaseli abomvu egazi, ivimbele ukuvuvukala futhi inamandla okulwa nengcindezi.
Ukukhiqizwa okunciphile kwe-aldosterone kanye ne-cortisol kubangela izimpawu ezivamile ku-Addison's disease njengokucindezeleka, ukukhathala, ukungathandi ukudla noma i-anorexia, ukuhlanza, ukwehlisa isisindo, isifo sohudo lwe-canine, indle enegazi, ukulahleka kwezinwele noma i-alopecia, ukwanda kokuchama, ukoma okwandayo, ukushaya ngamandla, ukomisa amanzi emzimbeni, isigqi senhliziyo esingajwayelekile, i-hypoglycemia, ubuhlungu esiswini futhi i-hyperpigmentation yesikhumba.
Ukuxilongwa kwesifo i-Addison
Isifo i-Addison futhi uvame ukutholakala lapho kuvela inkinga ye-Addisonian, okuthile kwenzeka lapho lesi sifo sesifikile esigabeni esibucayi ngakho-ke izinja ziveza izimpawu ezimele usongo empilweni yazo, njengokushaqeka nokuwa.
Lapho inkinga ye-Addisonia isisimeme, odokotela bezilwane kuzodingeka benze izivivinyo eziningi ukuze bakwazi thola imbangela yokuwa kanye nokunqabela noma iyiphi enye imbangela. Ngalesi sizathu, ukuhlolwa kwegazi kufanele kwenziwe enjeni yethu kanye ne-biochemistry ephelele futhi ngendlela efanayo kungadingeka ukuhlaziywa komchamo.
I-anemia kanye namazinga angajwayelekile we-potassium ne-urea egazini, ngaphandle kwamazinga angajwayelekile we-sodium, calcium, kanye ne-chloride egazini, yizimpawu zesifo sika-Addison. I-Urinalysis inamandla okuveza ngokulinganayo ifayela le- ukugxila komchamo ophansi futhi udokotela wezilwane anganikeza inja yethu i-electrocardiogram ukubheka ukuthi alukho yini ushintsho enhliziyweni yenja yethu.
Ukuhlolwa okucacile kwalesi sifo ukuhlolwa kwe- ukukhuthazwa kwe-corticotropin, okuphathelene nokulawula ukusebenza kwezindlala ze-adrenal ngokwethulwa kwehomoni yokwenziwa i-ACTH. Odokotela bezilwane balinganisa ukuhlushwa kwe-cortisol ngaphambi nangemva kokuphathwa kwayo, okubavumela ukuthi bazi ukuthi izindlala ze-adrenal zisebenza kahle yini.
Ukwelashwa nokunakekelwa kwesifo i-Addison ezinjeni
Enye yezinto zokuqala odokotela bezilwane abazenzayo ukwelapha isifo i-Addison ezinjeni ukuxazulula inkinga ye-Addison.
Ukwenza lokhu, inja kufanele ilaliswe esibhedlela futhi nayo kufanele ithole ukwelashwa okunamandla ukuze ilawule izimpawu zenkinga. Lapho inja yethu isiphuma engozini futhi ikwazile ukuzinza, ngokushesha i-vet yakho ingakunika umuthi ongena esikhundleni se-hormone ukwazi ukusiza inja yethu ngokushoda.
Ngokuvamile kunezidakamizwa ezingaphezu kwesisodwa zesifo se-Addison ezinjeni, umjovo oyi-mineralocorticoids osetshenziswa njalo ngenyanga futhi nalowo oyi-steroids osetshenziswa nsuku zonke. Ngaphandle kwalokho udokotela wezilwane uvame ukwenza ukuhlolwa kwegazi minyaka yonke noma isemester ngayinye ukuze aqiniseke ukuthi umuthi uyawenza ngempela umsebenzi wawo ngendlela efanele.
Isifo i-Addison ezinjeni siyinto engeke yelapheke. Inja yethu kuzodingeka athathe ama-hormone esikhundleni iminyaka esele yokuphila kwakhe, futhi kungenzeka kakhulu ukuthi kuzodingeka ukwenza ushintsho kumthamo eminyakeni edlule, ikakhulukazi lapho inja idlula ezikhathini zokuxineka.
Kubaluleke kakhulu ukuthi singazami ukulungisa umuthi ngaphandle kokubonisana nodokotela wezilwane kuqala, ngoba Lokhu kungadala okunye ukungalingani kumahomoni enja yethu.
Ukuze sikwazi ukuthola umthamo okhonjisiwe wokwelapha isifo i-Addison kudinga isikhathi futhi njengabanikazi kumele sikulungele vakashela udokotela wezilwane kaningi ngenkathi inyanga yokuqala yokuxilongwa idlula, ukuze ngale ndlela udokotela wezilwane abe nethuba lokukala amazinga ama-hormone kanye nama-electrolyte enja yethu.
Ngemuva kokwenza konke lokho, kuzofanele sithathe inja yethu kanye ngenyanga ukuyibeka umjovo wokufaka i-hormone kanye nokwenza isiqiniseko sokuthi silandela inqubo yokwengeza yemithi udokotela wezilwane angasimisela yona.