El Cushing's chirwere Ichi chirwere che endocrine chinoitika kana muviri wembwa uchivanza kuwandisa kwecortisol. Nekudaro, avo vane chekuita nekugadzirwa kwayo idrenal gland, iri padyo neitsvo. Ichi chirwere chinowanzoitika mune imbwa diki dzerudzi dzakura kupfuura makore matanhatu, uye kunyangwe isina mushonga, haifanirwe kudzora hupenyu hwechipfuwo kana ichigamuchira kurapwa kwakakodzera.
Iyo inonziwo hyperadrenocorticoidism, kusagadzikana uku kunogona kuve kwakakonzerwa nezvinhu zvinoverengeka. Inowanzozivikanwa ndeyekuonekwa kwe mamota mune yepituitary gland, uye chechipiri, munzvimbo ine adrenal. Kuenderera mberi kana kunyanyisa kutarisirwa kwecorticosteroids kunogona zvakare kutungamira mukukura kwechirwere ichi. Kusvikira zuva ranhasi, hazvina kuratidzwa kuti zvine chero chinhu chemagetsi.
El Cushing's chirwere inoisa panjodzi hupenyu hwembwa kana ikasagamuchira kurapwa. Zviratidzo zvaro zvinowanzoenda zvisingaonekwe sezvo zvine kukanganisa zvine chekuita nezera rembwa remhuka, asi chokwadi ndechekuti vanoisa njodzi huru kuhutano hwavo. Pakati pavo tinowana iyo symmetric alopecia (pamativi ese emuviri nemuswe), inozviratidza kana chirwere chiri padanho repamberi.
Pakutanga kuoneka zvimwe zviratidzo sekuzvimba kwemudumbu, nyota yakawandisa, kuda kudya zvakanyanya, kushaya simba kwemhasuru, kushaya hanya, dermatitis, kufema uye kuonda mukurema kweganda. Nekudaro, iyo imbwa haifanire kuratidza zvese izvi zviratidzo, izvo zvinonetsa kuona nekuti mazhinji acho anoenderana nedanho rekuchembera.
Iyi syndrome inoonekwa kuburikidza nemuyedzo dzakasiyana. Chekutanga pane zvese, zvakafanira kuita ongororo yeropa uye weti, kwatinogona kuona zviratidzo zvidiki zvine chekuita nechirwere ichi. Izvo zvakakoshawo kuti uite dumbu X-ray uye ultrasound, ayo anoshanda kwazvo pakuongorora saizi yeitsvo matinji. Nekudaro, kune zvimwe zvakatarwa bvunzo senge ACTH kukurudzira bvunzo uye dexamethasone yekudzvinyirira bvunzo, iyo inoyera mwero weropa wecortisol.
Kune akasiyana marapirwo eCushing's Syndrome, ayo anoenderana nehunhu hwenyaya imwe neimwe. Dzimwe nguva a kuvhiya kupindira kuitira kuti ubvise bundu rinokonzera dambudziko, uye pane dzimwe nguva kurapwa kunobva pane chemotherapy kana yakasanganiswa radiation kurapwa. Iko manejimendi yemishonga dzakasiyana zvakare kwakajairika.