La Isifo sika-Addison ezinjeniEsinokuyazi ngegama le-hypoadrenocorticism, siyinxalenye yesinye sezifo ezinokulandelelana kakhulu ezinjeni, nangona ngethamsanqa lolona nyango lufanelekileyo, izinja ezifumene isifo kwesi sifo zinokubakho ukuba nexesha lokuphila eliqhelekileyo ngokupheleleyo.
Ukuba siyabona ukuba isilwanyana sethu sigula rhoqo kwaye amayeza esiwanike wona awabangeli mpembelelo, kunokwenzeka ukuba unesifo sika-Addison, kungenxa yesi sizathu ukuba kweli nqaku sikulethela nonke ulwazi oluyimfuneko malunga iimpawu, unyango kunye nokhathalelo kwesi sifo.
Yintoni isifo sika-Addison?
Isifo iAddison sizinja, esinegama lenzululwazi hypoadrenocorticism, sisifo esibi kakhulu echaphazela enye okanye zombini iidrenal glands zenja yethu, ezizezona zibekwe ngokuchanekileyo kwizintso.
Nantoni na ebangela umonakalo kwiincindi zeadrenal isenokuba ngunobangela wesifo sika-Addison.
Izinja ezinesi sifo azinakho ukuvelisa isixa esifunekayo sehomoni yeadrenal (eyaziwa ngokuba yi ukungoneli kwe-canine adrenal) kwaye ngenxa yoko imele into ebaluleke kakhulu kwinkalo yokusebenza komzimba. Oku kubangela ukuba amanqanaba eswekile, isodiyam, ipotassium kunye nekloride efumaneka egazini azinalo ulawulo oluyimfuneko, olunokubangela ukomisa inja yethu kunye neengxaki ezinkulu kumalungu abalulekileyo omhlobo wethu onoboya, ngokukodwa Intliziyo.
Yintoni ebangela isifo sika-Addison kwizinja
Ngokubanzi, kwaye phantse kuzo zonke iimeko, yintoni enokubangela Isifo iAddison ezinjeni yinto engekaziwa.
Oogqirha bezilwanyana banorhano lokuba kwiimeko ezininzi esi sifo kungenxa yesiphumo senkqubo yokuzimela. Isifo sika-Addison ngokufanayo Ingabangelwa kukutshatyalaliswa kwe-adrenal glandNokuba sisisu semastastatic, sisifo sentliziyo, ukopha, sisifo segranulomatous, ziiarhente zeadrenolytic, ezinje ngechiza mitotane okanye ngamanye amayeza anje nge trilostane, ekwaziyo ukuthintela ii-enzymes zeadrenal.
Ukuba kukho nantoni na ethintela ukusebenza kakuhle kwamadlala adrenal, umzimba awusenawo amandla okuvelisa i-glucocorticoids kunye ne-mineralocorticoids, ngakumbi i-aldosterone kunye ne-cortisol. Ngoko ke, oku kubangela inani elikhulu leempawu kwaye kwiimeko ezinzima kakhulu zezinja ezinesifo se-Addison, ukufa kwenzeka.
Izazinzulu azinalo ulwazi ngqo yintoni enokubangela isifo sika-AddisonNangona kunjalo, nayiphi na inja nokuba yeyoluphi na uhlobo kunye nobungakanani inokubakho kwesi sifo. Nangona kunjalo, iintlobo ezithile zezinja zihlala zithambekele ekuphuhliseni isifo sika-Addison kwaye zezi zilandelayo:
- Ipoodle
- Indawo emhlophe
- Umsele omkhulu
- Iindevu Collie.
- Inja yaManzi yasePortugal
- INova Scotia terrier.
- I-Irish Soft Camera Camera Terrier
Isifo iAddison inesakhono sokuchaphazela izinja ngaphandle kohlobo lwazo, ubudala okanye isiniNangona kunjalo, iba yinto eqhelekileyo kwizinja ezincinci, iimazi nakwabo baneminyaka ephakathi.
Iimpawu zesifo sika-Addison
Xa isifo sika-Addison sivela ezinjeni, sikwenza oko ngokuthe ngcembe kwaye kudla ngokuba nzima kakhulu ukufumanisa isifo ngenxa yenani elikhulu leempawu ezinxulumene nesi sifo.
Ngokubanzi, izinja ezinesifo sika-Addison zinakho ukukhula kweziqendu ezomeleleyo zesisu, ukulahleka kwesidlo, ukulahleka kancinci kwemeko yomzimba, kwaye kunokubangela noxinzelelo. Kubaluleke kakhulu ukuba siyigcine engqondweni loo nto Iimpawu zeZifo zeAddison kwiZinja, kuba ezi zinokukhula okanye zinciphise.
Imveliso enciphileyo ye-aldosterone inefuthe elibonakalayo emzimbeni. Le yinto ekhokelela kutshintsho kumanqanaba e-serum e-potassium ye-sodium kunye ne-chloride kwaye zinokuchaphazela izintso. Oku ngendlela efanayo kunokubangela iingxaki entliziyweni nakwinkqubo yokujikeleza kwegazi.
ICortisol yenye yefayile ye- iihomoni ze-steroid ezibaluleke kakhulu esichaphazeleka sisifo sika-Addison, esidlala indima ebaluleke kakhulu kwizicubu zomzimba wenja yethu. Oku linoxanduva lokulawula ukuveliswa kweswekile, kodwa ikwalawula imetabolism, inoxanduva lokwaphula amanqatha kunye neeproteni, ilawule uxinzelelo lwegazi, ivuselele ukwakheka kweeseli ezibomvu zegazi, ithintele ukudumba kwaye ikwanakho ukulwa noxinzelelo.
Ukuhla kwemveliso yealdosterone kunye necortisol kubangela Iimpawu eziqhelekileyo kwisifo sika-Addison ezinje ngoxinzelelo, ukonqena, ukungabi namdla wokutya okanye ianorexia, ukugabha, ukwehla kobunzima, urhudo lwe-canine, izitulo ezinegazi, ukulahleka kweenwele okanye i-alopecia, ukwanda kokuchama, ukonyuka okunxaniweyo, ukubetha komoya obuthathaka, ukuphelelwa ngamanzi emzimbeni, isingqi sentliziyo esingaqhelekanga, i-hypoglycemia, iintlungu esiswini kunye kunye nokutshiswa kwesikhumba.
Ukuchongwa kwesifo iAddison
Isifo iAddison kwaye uqhele ukufumanisa ukuba kwenzeka ingxaki yeAddisonia, into ethi kwenzeka xa esi sifo sifikelele kwinqanaba elibi kwaye ke izinja zineempawu ezibonisa isoyikiso ebomini babo, ezinje ngomothuko kunye nokuwa.
Xa ingxaki ye-Addisonian izinzile, oogqirha bezilwanyana kuya kufuneka benze iimvavanyo ezininzi ukuze bakwazi Misela unobangela wokuwa kunye nokugweba nasiphi na esinye isizathu. Ngesi sizathu, uvavanyo lwegazi kufuneka lwenziwe kwinja yethu kunye ne-biochemistry epheleleyo kwaye ngendlela efanayo kufuneka uvavanyo lwe-urinalysis.
I-Anemia, kunye nenqanaba elingaqhelekanga le-potassium kunye ne-urea egazini, ngaphandle kwamanqanaba angaqhelekanga esodiyam, ikhalsiyam, kunye nekloride egazini, ziimpawu zesifo iAddison. Uhlalutyo lomchamo lunakho ukuveza ngokulinganayo iifayile ze- iindawo eziphantsi zomchamo Kwaye ugqirha wezilwanyana unokunika inja yethu i-electrocardiogram ukukhangela ukuba akukho lutshintsho na kwintliziyo yenja yethu.
Uvavanyo oluchanekileyo lwesi sifo luvavanyo lwe Ukukhuthaza i-corticotropin, emalunga nokulawula ukusebenza kwamadlala ngokwenziwa kwehomoni yokwenziwa ye-ACTH. Oogqirha bezilwanyana balinganisa uxinzelelo lwe-cortisol ngaphambi nasemva kokuba ilawulwe, ebavumela ukuba bazi ukuba amadlala asebenza kakuhle.
Unyango kunye nokunyamekela isifo sika-Addison kwizinja
Enye yezinto zokuqala ezenziwa ngoogqirha bezilwanyana ukunyanga isifo sika-Addison ezinjeni ukusombulula ingxaki yeAddison.
Ukwenza oku, inja kufuneka ilaliswe esibhedlele kwaye kufuneka inyangwe kakhulu ukuze ilawule iimpawu zentlekele. Nje ukuba inja yethu iphume engozini kwaye ikwazile ukuzinza, kwangoko ugqirha wezilwanyana unokukunika ichiza elinokubuyisela i-hormone ukuze sikwazi ukunceda inja yethu ngokusilela.
Kukho iziyobisi ezingaphezulu kwesinye kwisifo iAddison kwizinja, inaliti ene-mineralocorticoids esetyenziswa rhoqo ngenyanga kunye neyo-steroids esetyenziswa yonke imihla. Ngaphandle kwaleyo ugqirha wezilwanyana uhlala esenza iimvavanyo zegazi minyaka le okanye kwisemester nganye ukuze uqiniseke ukuba iyeza liyawenza umsebenzi walo ngokuchanekileyo.
Isifo iAddison kwizinja yinto enganyangekiyo. Inja yethu Kuya kufuneka uthathe iihormone ezithatha indawo kwiminyaka eseleyo yobomi bakhe, kwaye kunokwenzeka ukuba kuyakufuneka ukuba kwenziwe uhlengahlengiso kwidosi kwiminyaka edlulileyo, ngakumbi xa inja ihamba ngamaxesha oxinzelelo.
Kubaluleke kakhulu ukuba singazami ukulungelelanisa amayeza ngaphandle kokubonisana okokuqala nodokotela wezilwanyana, kuba Oku kunokubangela okunye ukungalingani kwihomoni yenja yethu.
Ukuze sikwazi ukufumana idosi ebonisiweyo yokunyanga isifo sika-Addison kufuna ixesha kwaye njengabanini kufuneka sikulungele ndwendwela ugqirha wezilwanyana rhoqo Ngelixa inyanga yokuqala yoxilongo iyadlula, ukuze ngale ndlela ugqirha wezilwanyana abe nethuba lokulinganisa amanqanaba ehomoni kunye neeelectrolyte zenja yethu.
Emva kokwenza konke oko, kuyakufuneka sithathe inja yethu kanye ngenyanga ukubeka i inaliti yokubuyisela i-hormone kwaye siqiniseke ukuba silandela inkqubo eyongezelelweyo yamayeza asenokuyalelwa ngugqirha wezilwanyana.