La imysthenia gravis sisifo se-neuromuscular esichaphazela inja. Ngethamsanqa, kunqabile kodwa kusabalulekile ukwazi ukuba kubangelwa yintoni, zithini iimpawu kunye nonyango oluboniswe ngugqirha wezilwanyana.
Njengophawu oluphambili lwesi sifo sifumana ubuthathaka kwimisipha kuwo wonke umzimba wenja, inonyango oluyindaba ezimnandi, nangona kunjalo, ukuxela kwangaphambili yenye into kwaye oku kuya kuxhomekeka kwimeko nganye apho kuyakubakho izinja ezikwaziyo ukubuyela kwimeko yesiqhelo kwaye ezinye ezingayi kubaleka ngekamva elifanayo.
Yintoni imastastia gravis?
Iingcali zibonisa ukuba esi sifo sizibonakalisa xa kukho ukunqongophala kwee-acetylcholine receptors, eyokugqibela yimolekyuli enomsebenzi we-neurotransmitter oveliswa kwii-neuron eziyinxalenye ebalulekileyo yenkqubo yemithambo-luvo. Ezi zinoxanduva lokudlulisa impembelelo yentliziyo.
Ii-receptors zibekwe ikakhulu kwiziphelo ze-neuromuscular ze-peripheral kunye ne-central system ye-nervous. Ukuyiqonda ngcono, xa inja ishukumisa nasiphi na isihlunu somzimba, a Ukukhululwa kwe-acetylcholine Ngayo iodolo yentshukumo iya kudluliswa, enkosi kubamkeli bayo.
Ngenxa yoko, ukuba azonelanga ezi receptors okanye azisebenzi kakuhle, ukuhamba kwesihlunu akuyi kwenzeka okanye kuya kwenza ngokungalunganga. Kungalo mzuzu apho i imysthenia gravis, ethi Inokubonakaliswa okwahlukileyo esiza kuthi sinike iinkcukacha ngezantsi.
Esi sifo sichaphazela kuphela izihlunu ezenza umsebenzi wokuginya ukutya. Inkqubo ye- Isizalo se-myasthenia gravis, exhaphake kakhulu kwiintlobo ezinje nge Isipani sepringer okanye uJack Russell, ikwanelifa.
Emva koko kukho Ukufumana i-myasthenia gravis, exhaphake kwaye ikhuselekile kwizifo ezinje ngomalusi waseJamani, iGold retriever, iDachshund, Ukufunyanwa kweLabrador kunye ne-Scottish terrier, engeyena mqobo kuyo ukuzibonakalisa kwezinye iintlobo.
Xa sithetha ngamajoni omzimba, sibhekisa kuwo ukuhlaselwa kunye nokutshatyalaliswa kwee-antibodies zenja ngokuchasene ne-acetylcholine receptors yabo, imeko enokwenzeka kwiminyaka emibini ubudala, eyokuqala ukusuka kunyaka we-1 ukuya kwi-4 kunye neyesibini ukusuka kwi-9 ukuya kwi-13 iminyaka.
Zithini iimpawu?
Kukho ubuthathaka obuqhelekileyo obuhlala buba nzima ngenxa yokuzivocavoca. Kubonakala ngakumbi kwimilenze yangasemva kuba xa uzama ukuphakama okanye ukuhamba iya kubonisa ubunzima obukhulu kwaye iya kugungqa.
Ukuba imysthenia gravis ijolise, ingxaki iya kubekwa ekuginyeni apho inja iya kubona khona ukusebenza kwezihlunu eziyilungelelanisileyo. Oku iyakuthintela inja ekugingeni ukutya okuqinileyo ukusukela ukuba umqala uya kuba mkhulu kwaye uhluthwe. Xa inja izama ukuginya ukutya, inokuphelela emiphungeni ngenkqubo yokuphefumla, ibangele ukonyukelwa sisifo semiphunga.
Unyango
Into yokuqala ekufuneka uyenzile kukuya kugqirha wezilwanyana ngazo naziphi na iimpawu ezenza ukuba ukrokre ukuba inja yakho inesi sifo. Ngalo nto Ingcali iya kusebenzisa uhlalutyo novavanyo olufunekayo evumela ukuba kuchongwe isifo semithambo-luvo. Ngapha koko kukho iimvavanyo ezininzi zokufikelela kuvavanyo oluchanekileyo.
Emva koko, isigaba sonyango siyakwenziwa, esiqulathe ukulawulwa kwamachiza anceda ukunyusa amanqanaba e-acetylcholine kwii-receptors kwaye ngale ndlela kuphuculwe ubuthathaka kwezihlunu, nto leyo eme ngaphandle kwesi sifo izinja.
Ukubonelela ngonyango kwi-canine, ugqirha wezilwanyana uya kubonisa ukhetho kwaye loluphi olona lufanelekileyo. Yi Kananjalo inokunikezwa ngenaliti okanye ngomlomo. Idosi ekhuthazwayo iya kuxhomekeka kwimisebenzi yomhlobo wethu othembekileyo kwaye oku kufuneka kulawulwe ngokungqongqo kwaye kulandelwe yingcali. Kukho iimeko apho unyango luza kuba lolwexeshana, ngelixa kwezinye ii-canines lubalulekile ebomini.
Into ebalulekileyo malunga nolawulo lwezilwanyana kukuba i-megaesophagus eqhelekileyo ye-myasthenia gravis iya kuba nakho ukulawulwa okanye ukunyangwa. Umgcini wesilwanyana kufuneka akunyamekele ukondla ekucetyiswa ukuba iphantse ibe lulwelo okanye ngokupheleleyo, isikhongozeli esinokutya kufuneka sibekwe phezulu kwaye ukuba kukho naziphi na iingxaki zokuphefumla ezibonakala, kufuneka kusiwe kwangoko kugqirha wezilwanyana.
Esi sifo sinokuhamba ne-canine hypothyroidism, nangona kunjalo, esi sifo sinokunyangwa ngehomoni ngaphandle kwengxaki. Esinye isifo esidibene ne-canine myasthenia gravis sisisu se-thymus, Eli lidlala elidityaniswa nenkqubo ye-lymphatic yenja. Isisombululo ngotyando kwaye ngethamsanqa izinga leziganeko liphantsi kakhulu.
Ngaba siyanyangeka isifo?
Xa ifunyenwe ngexesha, ngokuxilongwa ngokuchanekileyo kunye nokusetyenziswa kwonyango, ukuxela ukubuyisela kwakhona kulungile. Nangona kunjalo, kukho into enefuthe kwaye leyo yimpendulo yenja kunyango.
Kwiimeko ezininzi ukubuyiswa kugqityiwe Naxa sithetha ngokugxila kwe-myasthenia gravis apho kunokwenzeka khona nge-100% ukufumana inja ukuba iginye ngokuqheleke ngokupheleleyo. Ngokubhekisele kwi-megaesophagus, kukho iimeko apho ibandakanya khona iingxaki ezikhokelela kwisifo esigciniweyo, nokuba imeko iphantsi konyango, inokubonisa iingxaki ezenza mandundu iimpawu.
Ukuchongwa kwangoko kungasindisa inja iingxaki ezininzi zempilo kunye neengxaki, ngale ndlela kwaye kuba uyazi kancinci malunga nesi sifo kubalulekile ukuba xa kukho iimpawu zeli okanye nasiphi na isifo okanye isifo ongena kuso Nxibelelana nogqirha wezilwanyana.
Okukhona unomdla kwindlela inja eziphatha ngayo, ngokukhawuleza uyakubona nayiphi na imiqondiso. Kwangokunjalo, ingcali kwizifo zemihlathana ngalo lonke ulwazi onokuluhambisa kunye neempawu eziziswa sisilwanyana, kuya kuba lula ukwenza isifo kunye nokusetyenziswa konyango ngokwetyala. Ngoko ungoyiki esi sifo kwaye usinqande ngokukhawuleza.