La Isifo seVon Willebrand ukuphazamiseka okuzuzwe njengefa okuthinta kakhulu ukugeleza kwegazi, njengoba kubonakala ngokushoda kwe-Von Willebrand factor, i-glycoprotein evumela amaplatelet ukuthi anamathele emithanjeni yegazi ngesikhathi senqubo yokujiya. Lokhu kubangela ukopha njalo nokuphulukiswa kwesilonda okunzima.
Lokhu kuyiphutha okuhlobene ne- ukujiya kwegazi okuvame kakhulu phakathi kwezinja, ngokuba yiGerman Shepherd, iGolden Retriever, iPoodle, iDoberman kanye neShetland Sheepdog ezinye zezinhlobo ezivame kakhulu kuzo. Ngokwemvelo, kubangelwa ukuguqulwa kwezakhi zofuzo okungenzeka kubesilisa noma kwabesifazane ngokungaqondakali, futhi kubonakala ngezimpawu ezifana nalokhu okulandelayo:
• Ukopha ezinsinini nasemakhaleni.
• Ukopha esitokisini kanye nomchamo.
• Ukulimaza esikhumbeni ngaphandle kwesizathu.
• Ukopha ngokweqile enxebeni elincane.
• Ukopha ngokweqile esithweni sangasese ngesikhathi sokushisa noma sokubeletha.
• Ukushoda kwegazi.
Lezi zimpawu zenzeka kusukela onyakeni owodwa ubudala futhi kuya ngamandla azo zingaba yingxenye yesifo sokuqala i-Von Willebrand Type Type, Type 1 noma Type 2. Ngenhlanhla, ezimweni eziningi izimpawu imnene kakhulu, ukuze izikhathi eziningi lesi sifo singatholakali size sitholwe kuze kube yilapho isilwane singangenelelwa ngokuhlinzwa okuthile. Kodwa-ke, uma sisola ukuthi inja yethu ingahlushwa yiyo, into efanele ukwenziwa ukuxhumana nodokotela wezilwane.
Lesi sifo sitholakala ngokuhlolwa okwaziwa ngokuthi "Isikhathi sokopha se-buccal mucosa" (MBST), futhi siqukethe ukubuka ukuthi isilonda esincane esisezinsinini ze-canine sithatha isikhathi esingakanani ukuvimba. Kufanele ngaso sonke isikhathi kwenziwe ngudokotela wezilwane, naye ozokwenza ukuhlolwa kwegazi ukuthola iphesenti le-Von Willebrand factor ekhona kulo. Uzophinde enze ukuhlolwa kwe-DNA ukukhomba izinja ezinalezi zimpawu nabathwali besifo; Lokhu kuhlolwa kuthembeke kunakho konke ukuxilongwa.
Alikho ikhambi lalokhu okungavamile, kepha izimpawu zakho zingalawulwa ngempumelelo enkulu ngokusebenzisa imithi. Isikhathi esiningi, inikezwa ngaphambi kokuhlinzwa noma ngemuva kokuhlinzwa, nangemva kokulimala noma ingozi. Ezimweni ezimbi kakhulu, ukumpontshelwa igazi kuyadingeka.